Spanish researchers have created a powerful new open-source tool that helps uncover the hidden genetic networks driving cancer. Called RNACOREX, the software can analyze thousands of molecular interactions at once, revealing how genes communicate inside tumors and how those signals relate to patient survival. Tested across 13 different cancer types using international data, the tool matches the predictive power of advanced AI systems—while offering something rare in modern analytics: clear, interpretable explanations that help scientists understand why tumors behave the way they do.

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OpenAI introduces a new framework and evaluation suite for chain-of-thought monitorability, covering 13 evaluations across 24 environments. Our findings show that monitoring a model’s internal reasoning is far more effective than monitoring outputs alone, offering a promising path toward scalable control as AI systems grow more capable.

OpenAI is updating its Model Spec with new Under-18 Principles that define how ChatGPT should support teens with safe, age-appropriate guidance grounded in developmental science. The update strengthens guardrails, clarifies expected model behavior in higher-risk situations, and builds on our broader work to improve teen safety across ChatGPT.

OpenAI shares new AI literacy resources to help teens and parents use ChatGPT thoughtfully, safely, and with confidence. The guides include expert-vetted tips for responsible use, critical thinking, healthy boundaries, and supporting teens through emotional or sensitive topics.

OpenAI and the U.S. Department of Energy have signed a memorandum of understanding to deepen collaboration on AI and advanced computing in support of scientific discovery. The agreement builds on ongoing work with national laboratories and helps establish a framework for applying AI to high-impact research across the DOE ecosystem.

GPT-5.2-Codex is OpenAI’s most advanced coding model, offering long-horizon reasoning, large-scale code transformations, and enhanced cybersecurity capabilities.

GPT-5.2-Codex is OpenAI’s most advanced coding model, offering long-horizon reasoning, large-scale code transformations, and enhanced cybersecurity capabilities.

OpenAI is launching the OpenAI Academy for News Organizations, a new learning hub built with the American Journalism Project and The Lenfest Institute to help newsrooms use AI effectively. The Academy offers training, practical use cases, and responsible-use guidance to support journalists, editors, and publishers as they adopt AI in their reporting and operations.

Developers can now submit apps for review and publication in ChatGPT, with approved apps appearing in a new in-product directory for easy discovery. Updated tools, guidelines, and the Apps SDK help developers build powerful chat-native experiences that bring real-world actions into ChatGPT.

A data-driven look at enterprise AI adoption, showing how organizations move from experimentation to real productivity gains and new capabilities.

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OpenAI introduces FrontierScience, a benchmark testing AI reasoning in physics, chemistry, and biology to measure progress toward real scientific research.

OpenAI introduces a real-world evaluation framework to measure how AI can accelerate biological research in the wet lab. Using GPT-5 to optimize a molecular cloning protocol, the work explores both the promise and risks of AI-assisted experimentation.

The new ChatGPT Images is powered by our flagship image generation model, delivering more precise edits, consistent details, and image generation up to 4× faster. The upgraded model is rolling out to all ChatGPT users today and is also available in the API as GPT-Image-1.5.

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BNY uses OpenAI to expand AI adoption enterprise-wide through Eliza, where 20,000+ employees build AI agents that improve efficiency and client outcomes.

OpenAI shipped Sora for Android in 28 days using Codex. AI-assisted planning, translation, and parallel coding workflows helped a nimble team deliver rapid, reliable development.